43. Approximately how many cases of late sero-negative Lyme patients will become sero-positive after successful treatment?

It has been reported that increasing numbers of seronegative patients who were diagnosed clinically and treated for Lyme disease, converted to seropositive after the completion of antibiotic therapy. Unfortunately, physicians unfamiliar with Lyme disease are refusing treatment to seronegative patients even when they have active symptoms. The CDC states Lyme disease is a clinical diagnosis and negative tests should not be used to rule out diagnosis.

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